Proton Therapy for Cancer Treatment in India - Apollo Hospitals

 

What is Proton Therapy?

Proton Therapy is an advanced and highly precise form of radiation therapy used to treat various types of cancer. Unlike traditional X-ray radiation (photon therapy), which releases radiation along its entire path through the body, Proton Therapy uses positively charged particles “protons” that release their energy only when they reach a specific depth in tissue. This means proton beams can be precisely targeted to deposit maximum energy directly in the tumor while sparing healthy tissue around it.

This characteristic makes Proton Therapy especially valuable for treating cancers located near vital organs or in sensitive areas like the brain, spine, lungs, and eyes. It is also an excellent option for pediatric patients whose developing organs are particularly vulnerable to radiation damage.

The Proton Therapy procedure is non-invasive and painless. Each session typically lasts 15 to 30 minutes, and most patients tolerate it well with fewer side effects compared to conventional radiotherapy.

Apollo Hospitals is the first healthcare provider in South Asia offering Proton Therapy, placing India at the forefront of precision cancer care. Patients from across the country and abroad now have access to one of the world’s most advanced cancer treatments—without having to leave South Asia.

History of Proton Therapy

Proton Therapy was first proposed for medical use in 1946 by American physicist Robert R. Wilson. The early treatments were conducted in physics research centers in the 1950s and 1960s. However, the technique was limited to clinical trials until the 1990s, when the first hospital-based proton centers emerged in the United States and Europe. Today, with technological advancements in imaging and beam control, Proton Therapy has evolved into one of the most accurate and safest forms of radiation therapy available.
 Apollo Hospitals brought this revolutionary technology to South Asia, making it accessible to patients across India and neighboring countries through its state-of-the-art Proton Therapy facilities.

Why is Proton Therapy Done?

Proton Therapy is chosen when cancer requires precise targeting of radiation to avoid damage to surrounding healthy tissues and critical organs. It is particularly beneficial in cases where tumors are located:

• Close to vital structures (e.g., optic nerves, spinal cord, brainstem)
• In pediatric patients (to prevent long-term growth and developmental complications)
• In previously irradiated areas (where healthy tissues have already been exposed to radiation)
• In patients who require a second course of radiation (re-irradiation cases)

Doctors may recommend Proton Therapy when the risk of radiation-induced complications from conventional X-rays is unacceptably high, or when higher doses of radiation are needed to destroy a tumor effectively.

By delivering radiation in a more controlled way, Proton Therapy not only improves treatment precision but also reduces long-term side effects, improves quality of life, and in some cases, enhances survival outcomes.

Indications for Proton Therapy

Proton Therapy is typically indicated after careful evaluation of several clinical factors, including the type of cancer, its location, patient age, previous treatments, and general health.

Common clinical indications include:

• Tumors in sensitive or hard-to-reach locations (e.g., brain, spine, eye, skull base)
• Tumors near critical organs such as the heart, lungs, liver, or intestines
• Pediatric cancers, where growth, cognitive function, and organ development must be preserved
• Recurrent cancers, especially if a patient has already received radiation therapy in the past
• Cancers requiring high-dose radiation, where precision delivery minimizes collateral damage
• Patients with genetic syndromes that increase sensitivity to radiation (e.g., Li-Fraumeni syndrome)

Before recommending the Proton Therapy procedure, patients at Apollo Hospitals undergo a thorough work-up that may include imaging studies (MRI, CT, PET), biopsy confirmation, and review by a multidisciplinary tumor board to ensure that proton therapy is both appropriate and beneficial.

How Does Proton Therapy Work?

Proton therapy works by harnessing the unique physical properties of protons—positively charged particles that, unlike traditional X-rays, deposit most of their energy at a precise point known as the Bragg Peak. This allows oncologists to target tumors with exceptional accuracy, delivering high doses to cancer cells while minimizing exposure to nearby healthy tissues.

Advanced Delivery Techniques at Apollo Proton Cancer Centre (APCC)

At the Apollo Proton Cancer Centre (APCC) in Chennai, we go beyond the basic principles of proton therapy by using some of the most sophisticated delivery systems in the world. Our technology ensures sub-millimeter precision even in complex, hard-to-reach tumors.

Key technological advancements at APCC include:

• Pencil Beam Scanning (PBS): This highly refined technique delivers proton radiation in a narrow beam that "paints" the tumor layer by layer, sparing surrounding healthy tissues.
• Intensity-Modulated Proton Therapy (IMPT): A more advanced form of PBS, IMPT adjusts the intensity of the proton beam at every point. This allows for 3D dose sculpting—even around delicate structures like the optic nerve, brainstem, or spinal cord.
• Real-time Tumor Tracking: Tumors can move during treatment due to breathing or other bodily functions. APCC’s real-time monitoring systems track this motion and adapt beam delivery accordingly.
• Integrated Imaging Guidance: Advanced imaging such as CT and MRI is embedded into the treatment workflow, ensuring accurate tumor localization before and during every session.
• Dynamic Adaptation and Replanning: As a patient’s tumor changes in size or shape during treatment, our systems can re-optimize the treatment plan mid-course for continued precision.
• Sophisticated 3D Treatment Planning: Every treatment plan at APCC is generated using powerful algorithms that simulate multiple dose scenarios, allowing clinicians to choose the safest and most effective configuration.

This revised section enhances the global article by building upon the existing explanation rather than restating it. Let me know if you’d like this to be followed by a comparison table with traditional X-ray radiation (if not already in the article), or if you want to insert a visual flow diagram of the treatment planning and delivery process.

Is Proton Therapy the Same as Radiotherapy?

A common question among patients is whether Proton Therapy is just another form of radiation therapy. The answer is yes and no.

Technically:

Proton Therapy is a form of radiation therapy—but it uses protons instead of conventional X-rays (photons).

In Practice:

Proton Therapy is far more precise and safer than traditional radiotherapy, particularly for tumors located near critical organs or in children.

This Bragg Peak effect—where protons stop at the tumor without continuing through the body—is what makes Proton Therapy so uniquely powerful.

Apollo Hospitals, as South Asia’s first Proton Therapy provider, offers this technology across multiple metro cities in India, bringing global-quality care closer to home.

The Treatment Process at Apollo Proton Cancer Centre (APCC)

At the Apollo Proton Cancer Centre (APCC), every patient undergoes a carefully coordinated and highly personalized treatment journey. From the initial evaluation to post-treatment care, each step is designed for maximum precision, safety, and comfort.

Here’s how the process works:

1. Consultation and Initial Imaging

Your journey begins with a comprehensive consultation by our expert oncologists. This includes a thorough review of your diagnosis, medical history, and prior treatments (if any). Advanced imaging such as MRI, CT scan, or PET-CT is then performed to determine the exact location, size, and extent of the tumor.

2. Personalized Treatment Planning

A multidisciplinary team—including radiation oncologists, physicists, dosimetrists, and radiologists—works together to create a custom 3D treatment plan. This plan maps out the precise dose and trajectory of the proton beams to deliver optimal radiation to the tumor while protecting healthy tissues and critical structures nearby.

3. Simulation and Immobilization

Before treatment begins, a simulation session is conducted. During this phase:

• Immobilization devices (such as thermoplastic masks or vacuum cushions) are created to keep your body still in the exact same position during each session.
• The simulation ensures accurate alignment and prepares your body for treatment in a reproducible setup.

4. Proton Therapy Delivery

You will receive proton therapy in daily sessions, also known as fractions, over a period of 4 to 8 weeks, depending on your cancer type and stage.

• Each session lasts about 15 to 30 minutes, although the actual beam delivery takes only a few minutes.
• The treatment is non-invasive and painless—you remain awake and comfortable throughout.

Thanks to technologies like Pencil Beam Scanning, IMPT, and real-time tumor tracking, the radiation is delivered with exceptional precision.

5. Monitoring, Quality Checks, and Follow-Up

• Daily image guidance and quality assurance (QA) checks are performed before each session to confirm accurate targeting.
• Your care team regularly reviews your progress and adjusts the plan if needed.
• After treatment is completed, ongoing follow-up visits help monitor your recovery, manage any side effects, and track treatment outcomes.

Why This Process Matters

Every step of this treatment process is designed to:

• Maximize tumor control
• Minimize damage to surrounding healthy tissue
• Improve long-term outcomes and quality of life

This structured approach is especially beneficial for complex tumors and vulnerable patients such as children, elderly individuals, and those with tumors near critical organs.

What Types of Cancer Can Be Treated with Proton Therapy?

Proton Therapy is suitable for a wide range of cancers, especially those requiring high precision due to their proximity to critical organs or in patients who are more vulnerable to radiation toxicity.

Below is a comprehensive list of cancer types that can be effectively treated with Proton Therapy:

1. Pediatric Cancers

Children are ideal candidates due to their developing organs and increased sensitivity to radiation. Proton Therapy reduces the risk of secondary cancers and developmental issues.
At APCC, pediatric oncology is managed by a dedicated team of pediatric oncologists, radiation oncologists, child-life specialists, and supportive care staff to ensure gentle and effective care tailored for young patients.

• Medulloblastoma
• Ependymoma
• Rhabdomyosarcoma
• Retinoblastoma
• Neuroblastoma
• Wilms’ tumor
• Ewing sarcoma
• Osteosarcoma (in selected cases)

2. Brain and Central Nervous System Tumors

Proton Therapy protects cognitive function and critical structures like the optic nerves, brainstem, and pituitary gland.
APCC’s Neuro-Oncology Program combines cutting-edge proton delivery with expert neurosurgical planning to preserve neurological function and quality of life.

• Gliomas (low- and high-grade)
• Meningiomas
• Acoustic neuromas (vestibular schwannomas)
• Craniopharyngiomas
• Pineal gland tumors
• Chordomas and chondrosarcomas at the skull base

3. Head and Neck Cancers

These cancers are located near sensitive tissues like the eyes, ears, salivary glands, and cranial nerves.
The Head & Neck Oncology unit at APCC uses proton therapy to maximize tumor control while preserving speech, swallowing, and appearance.

• Nasopharyngeal carcinoma
• Paranasal sinus cancers
• Oropharyngeal cancer
• Laryngeal and hypopharyngeal cancers
• Salivary gland tumors
• Skull base tumors
• Recurrent head and neck cancers

4. Eye and Orbital Tumors

These cancers benefit greatly from the eye-sparing precision of proton beams.
Managed by the Ocular Oncology team at APCC, proton therapy offers effective tumor control while preserving vision and delicate eye structures.

• Intraocular melanoma (uveal melanoma)
• Retinoblastoma
• Orbital sarcomas

5. Prostate Cancer

Proton Therapy helps avoid damage to the bladder, rectum, and sexual organs, reducing urinary and sexual side effects.
APCC’s Uro-Oncology program utilizes high-precision proton therapy to treat prostate cancer effectively with minimal impact on bowel and sexual function.

• Localized prostate cancer
• High-risk and recurrent prostate cancer
• Patients with prior radiation or surgical history

6. Breast Cancer

Particularly useful in left-sided breast cancers, where the tumor is close to the heart.
APCC’s Breast Oncology team applies proton therapy to protect the heart and lungs while ensuring full tumor coverage—especially in patients with cardiac history or implants.

• Early-stage breast cancer
• Post-mastectomy patients with chest wall involvement
• Patients requiring nodal irradiation
• Patients with prior cardiac history or implants

7. Lung and Thoracic Cancers

Proton beams help avoid damage to lung tissue, heart, and esophagus.
At APCC, the Thoracic Oncology program leverages proton therapy’s precision to safely treat tumors in patients with compromised lung function or pre-existing heart conditions.

• Non-small cell lung cancer (NSCLC)
• Small cell lung cancer (in selected cases)
• Thymoma
• Mediastinal tumors
• Chest wall sarcomas
• Mesothelioma (selectively)

8. Gastrointestinal Cancers

Where conventional radiation poses risks to organs like the liver, pancreas, and bowel.
The GI Oncology team at APCC uses proton therapy to deliver high-dose treatment while protecting nearby digestive and metabolic organs from excess radiation.

• Esophageal cancer
• Pancreatic cancer
• Liver cancer (hepatocellular carcinoma, cholangiocarcinoma)
• Gastric (stomach) cancer
• Anal and rectal cancers (selectively)
• Retroperitoneal sarcomas

9. Gynecologic Cancers

While less common, Proton Therapy is considered in recurrent or complex cases.
APCC’s Gynecologic Oncology specialists use proton therapy for re-irradiation and advanced pelvic tumors to minimize toxicity to the bowel and bladder, especially in younger women.

• Cervical cancer (re-irradiation or locally advanced)
• Endometrial cancer (in complex pelvic anatomy)
• Vaginal and vulvar cancers

10. Genitourinary Cancers

Proton therapy can be used selectively when tumors are located near radiosensitive structures.
The Genitourinary Oncology team at APCC personalizes treatment for cancers of the bladder, kidney, and testis, ensuring optimal tumor control with minimal collateral damage.

• Bladder cancer (in selected patients)
• Kidney cancer (post-surgical bed irradiation)
• Testicular cancer (rare cases with retroperitoneal spread)

11. Sarcomas

Due to their location and radioresistance, Proton Therapy is often preferred.
APCC’s Bone and Soft Tissue Oncology program uses proton therapy to achieve limb preservation in sarcoma cases while minimizing long-term musculoskeletal damage.

• Osteosarcoma
• Ewing sarcoma
• Chondrosarcoma
• Rhabdomyosarcoma
• Leiomyosarcoma

12. Hematologic Cancers (Select Indications)

While blood cancers typically require systemic therapy, certain cases benefit from proton therapy:
In select cases, APCC’s Hemato-Oncology team incorporates proton therapy to control CNS or mediastinal disease when re-irradiation or targeted local control is needed.

• Recurrent lymphoma involving the CNS or mediastinum
• Leukemia with CNS involvement (pediatric)

13. Recurrent or Previously Irradiated Cancers

These patients have limited options, and Proton Therapy offers a safer path for re-treatment.
APCC specializes in re-irradiation protocols using proton therapy to minimize cumulative radiation burden while maintaining therapeutic effectiveness.

• Head and neck cancers
• Brain tumors
• Pelvic tumors
• Spine tumors

Contraindications for Proton Therapy: Who is not a Candidate

While Proton Therapy is a breakthrough in precision cancer treatment, it is not suitable for all patients or cancer types. There are specific medical and practical situations where the Proton Therapy procedure may not be recommended.

Common Contraindications:

1. Widespread or Metastatic Disease

Patients with cancer that has spread to distant organs (advanced stage) may not benefit from localized radiation like Proton Therapy. In such cases, systemic treatments like chemotherapy or immunotherapy are prioritized.

2. Tumors Not Suitable for Radiation

Some blood cancers—like most leukemias—do not typically require radiation or are better managed through systemic therapy. Proton Therapy is not generally indicated in such cases.

3. Prior Health Conditions

Severe heart disease, lung dysfunction, or kidney failure may limit a patient’s ability to lie still or undergo repeated treatment sessions, making Proton Therapy impractical or risky.

4. Tumors with Excessive Motion

Tumors that move significantly with breathing, such as those in the lung or upper abdomen, may be difficult to target unless advanced motion tracking systems are used. In such cases, conventional radiation with gating might be considered.

5. Inability to Tolerate Treatment Positioning

Patients with movement disorders, severe pain, or anxiety may struggle to remain in position during sessions. While mild cases can be managed, more severe limitations may lead to alternative treatment options.

6. Metal Implants Near the Tumor

Proton beams can be disrupted by metal objects (like pacemakers, surgical clips, or dental implants) that lie in the beam’s path. This may affect treatment accuracy.

At Apollo Hospitals, every patient is carefully assessed by a multidisciplinary oncology team. The goal is to ensure Proton Therapy is only recommended when it offers a clear advantage over other modalities, keeping safety and outcomes in focus.

How to Prepare for Proton Therapy

Preparation is a key part of the Proton Therapy procedure, ensuring treatment is safe, precise, and effective. At Apollo Hospitals, we guide each patient through a step-by-step process before the first session begins.

1. Medical Evaluation

You will meet with a radiation oncologist who will:

• Review your medical history
• Examine prior imaging or biopsy reports
• Discuss your current symptoms and health goals

2. Imaging and Simulation

Before beginning treatment, you will undergo a simulation session, which is essentially a treatment planning appointment. This step ensures that the proton beam targets your tumor with absolute accuracy.

• A simulation therapist will position you based on the area to be treated.
• A custom immobilization device may be created to help you stay still during each session. This could be a:
  • Mask for the head or face (for brain or neck tumors)
  • Cradle or mold for the spine, limbs, or torso
• Special ink marks (similar to small tattoos or freckles) may be placed on your skin or the device to align your body consistently throughout treatment. It is important not to wash off these marks.
• You will remain in this position while a series of imaging scans is performed, which may include:
  • CT scan
  • MRI
  • PET scan
  • X-rays

These images are used to build a 3D treatment plan that maps the exact shape, depth, and angle of the proton beam to match the tumor’s location and avoid surrounding tissues.

The entire simulation session usually takes 45 minutes to 1 hour, and is done on an outpatient basis.

3. Treatment Planning

After the simulation, a team of radiation oncologists, physicists, and dosimetrists creates a highly customized treatment plan using advanced software.

• The plan determines the number of sessions, beam angles, and energy levels required.
• Your doctor will explain the schedule, expected side effects, and safety precautions in detail.

4. Lifestyle Advice

• Stay hydrated before and during treatment
• Eat a protein-rich, balanced diet
• Avoid smoking, alcohol, and unprescribed supplements
• Try to maintain a positive mindset and get regular rest

At Apollo Hospitals, our care coordinators, oncology nurses, and nutrition experts ensure that every patient is fully supported throughout this preparation phase—medically, emotionally, and logistically.

Proton Therapy: Step-by-Step Procedure

Once your treatment plan is ready, your Proton Therapy journey begins. It is a non-invasive outpatient procedure, and most patients can continue normal activities during treatment.

Here’s what to expect:

1. Daily Sessions (Fractions)

• You’ll visit the hospital 5 days a week for several weeks.
• The number of sessions depends on the cancer type and plan (e.g., 25–35 sessions for many solid tumors).
• Each session lasts around 30–45 minutes, with the actual radiation delivery taking just a few minutes.

2. Positioning

• You’ll lie in the exact same position used during simulation.
• Immobilization devices will be applied.
• The treatment room is monitored by technicians from outside for safety.

3. Proton Beam Delivery

• The machine delivers proton beams from different angles using a rotating gantry.
• You won't see or feel the beam. The machine may buzz or hum.
• The beam hits the tumor at maximum intensity and stops without damaging tissues behind it.

4. Monitoring & Adjustments

• Imaging (X-rays or CT) may be done weekly to track tumor response or adjust the plan.
• Oncologists and support staff monitor for side effects and recovery progress.

5. Post-Treatment Follow-Up

After completion, your team will:

• Schedule follow-up scans (e.g., MRI or PET)
• Check for any late side effects
• Provide lifestyle or rehab support

Recovery after Proton Therapy is often smoother than with conventional radiation. Most patients report less fatigue, fewer skin issues, and better organ preservation, especially in sensitive areas like the brain, eye, spine, or pelvic region.

Where is Proton Therapy Available in India?

Apollo Hospitals in Chennai is the first and only private center in all of South Asia to offer Proton Therapy, making it the most advanced radiation treatment facility not just in India, but across the continent.

Apollo Proton Cancer Centre (APCC), Chennai

Located in Teynampet, Chennai, this state-of-the-art facility is internationally accredited and designed exclusively for advanced cancer care.

• Equipped with IBA Proteus®PLUS, a world-leading proton therapy system
• Staffed by a team of expert radiation oncologists, physicists, oncology nurses, and support specialists
• Offers integrated cancer care under one roof—including diagnostics, surgery, chemotherapy, and rehabilitation

Patients from India, Southeast South Asia, the Middle East, and Africa travel to Chennai to receive this breakthrough treatment, which was previously only available in a handful of developed countries.

Apollo’s Proton Therapy Centre places India on the global map for precision oncology, delivering world-class care to those who need it most—without having to travel abroad.

Access, Wait Times, and Referral Process in India

Proton Therapy is now available at multiple Apollo Hospitals across India, including Chennai, Hyderabad, Bangalore, Mumbai, Delhi, Kolkata, and Ahmedabad. To ensure timely and appropriate treatment, Apollo has streamlined the referral and scheduling process across all its centers.

Referral Process:

• Patients can be referred by a local oncologist, primary physician, or self-refer by contacting Apollo directly.
• Once contacted, the Proton Therapy coordination team gathers the patient’s reports and arranges for an expert review.

Wait Times:

• In most cases, the waiting period is short, usually 1 to 2 weeks, depending on the complexity of the case and availability of planning slots.
• Urgent or high-priority cases are expedited.

Support Provided:

• A dedicated international and domestic patient services team helps with appointments, medical visas, accommodation, and travel.
• Teleconsultations and second opinions are available before traveling to the treatment center.

Apollo’s integrated cancer care model ensures faster access, fewer delays, and seamless transition from diagnosis to treatment, especially for high-risk or time-sensitive cancers.

Technology at Apollo Hospitals

Apollo Hospitals uses the IBA Proteus®PLUS system, one of the most sophisticated Proton Therapy platforms in the world. This machine allows for:

• Pencil Beam Scanning (PBS)
• Intensity Modulated Proton Therapy (IMPT)
• Rotating gantry systems for delivering beams at multiple angles
• On-board imaging for millimeter-level alignment

The Proteus®PLUS system is in use at Apollo Proton Cancer Centre in Chennai, and similar technology is being implemented at other Apollo Proton Therapy centers across India. This ensures that patients benefit from world-class treatment technology without traveling abroad.

Benefits of Proton Therapy

Proton Therapy provides several advantages that make it a preferred choice for many types of cancer, particularly those located near critical organs or in children.

Key Advantages

Greater Precision
The proton beam stops at the tumor site, unlike traditional X-rays that continue beyond it. This limits damage to healthy tissues.

Fewer Side Effects
Because healthy tissues are spared, patients report fewer side effects such as fatigue, skin burns, nausea, or secondary damage to the heart, lungs, or brain.

Ideal for Pediatric Cancers
In children, Proton Therapy helps avoid developmental delays, learning difficulties, and the risk of secondary cancers later in life.

Safe for Recurrent Tumors
Proton Therapy is often used for patients who have previously received radiation and cannot tolerate further exposure from conventional methods.

Improved Long-Term Quality of Life
Because fewer organs are harmed, long-term quality of life is better preserved, especially for patients with brain, spinal cord, or head and neck tumors.

Shorter Recovery
With fewer side effects, most patients return to their normal lives more quickly.

Apollo Hospitals is the only private healthcare provider in South Asia offering Proton Therapy, combining this advanced treatment with world-class oncology care and internationally trained specialists.

Patient Eligibility Criteria for Proton Therapy

At Apollo Proton Cancer Centre (APCC), determining whether a patient is eligible for proton therapy involves a thorough, multidisciplinary evaluation. The goal is to ensure that patients receive the most effective, safest, and personalized form of cancer treatment possible.

Comprehensive Evaluation Process

Every patient undergoes a detailed medical assessment, which includes:

• Type and stage of cancer
• Tumor size, shape, and location
• Proximity to critical organs and structures
• Patient’s age and overall health
• Previous treatments, including radiation or surgery
• Potential for combining with other therapies (surgery, chemotherapy)

Advanced diagnostic imaging like high-resolution CT, MRI, or PET scans help visualize the tumor and its relationship with surrounding tissues. This helps in deciding whether proton therapy offers a clinical advantage over other radiation options.

Individual Case Review

Each case is presented before APCC’s multidisciplinary tumor board, which includes:

• Radiation oncologists
• Medical oncologists
• Surgical oncologists
• Radiologists
• Medical physicists
• Other specialists as needed

This team-based review ensures that proton therapy is recommended only when it offers clear benefits in terms of safety, precision, or outcome improvement compared to conventional radiation therapy.

Patient-Centric Considerations

Eligibility also accounts for non-clinical factors, including:

• The patient’s treatment preferences
• Willingness and ability to travel (if treatment is centralized)
• Financial planning and insurance support
• Post-treatment support requirements

Technical and Anatomical Suitability

Not all tumors can be optimally treated with proton therapy. Our planning team uses simulation scans and computerized treatment mapping to ensure:

• The tumor is accessible via proton beams
• Surrounding organs can be safely spared
• There is no excessive movement (e.g., due to breathing)
• The treatment position can be reliably reproduced daily

Side Effects and How to Manage Them

One of the most significant advantages of Proton Therapy is its ability to reduce damage to surrounding healthy tissues. This precision results in fewer and milder side effects compared to conventional radiation therapy. However, depending on the location of the tumor, some patients may still experience temporary symptoms.

At Apollo Proton Cancer Centre (APCC), side-effect management is not an afterthought—it's built into every stage of the treatment journey.

Common Side Effects by Treatment Area

These side effects are typically short-lived and resolve soon after therapy concludes.

Integrated Support System at APCC

To ensure maximum comfort and early symptom control, APCC offers a proactive and personalized care model that includes:

• Daily Monitoring: Our nursing and radiation teams check on patients before and after each session to identify emerging symptoms early.
• Weekly Physician Reviews: Radiation oncologists review your clinical status every week and modify supportive care accordingly.
• Oncology Nursing Care: Symptom-based care protocols are in place to address skin irritation, nausea, fatigue, or other effects as they arise.
• Nutrition Support: Dedicated clinical dietitians guide patients through treatment with tailored meal plans, especially if appetite or digestion is affected.
• Psychological Support: On-site psycho-oncology services help patients cope with emotional stress, anxiety, or mood changes.
• Physical Therapy and Rehabilitation: Where needed, physiotherapy is offered to improve strength, manage stiffness, and support recovery.

Patient Self-Care Tips

In addition to medical support, here are some simple ways patients can help manage mild side effects:

• Stay well-hydrated and eat small, nutrient-rich meals
• Get plenty of rest between sessions
• Use doctor-recommended skin lotions for dryness or redness
• Avoid sun exposure to the treated area
• Share any new or worsening symptoms immediately with your care team

Commitment to Comfort and Safety

At Apollo Proton Cancer Centre, side-effect management is personalized, continuous, and compassionate. Our holistic support system ensures that each patient receives not just advanced cancer treatment—but also the care, education, and reassurance needed to heal confidently.

Success Rate of Proton Therapy for Cancer

Proton Therapy has shown high success rates for many types of cancer, especially when used appropriately and in experienced hands. Success rates can vary based on the type and stage of cancer, patient age, and overall health, but clinical data has been promising.

Examples of Reported Success

• Pediatric brain tumors: Up to 85 to 90 percent disease control in localized tumors
• Prostate cancer: Over 90 percent five-year survival in early-stage cases
• Head and neck cancers: Comparable or superior tumor control with fewer complications
• Skull base tumors like chordomas: Better local control compared to traditional therapy

Apollo Hospitals, with its dedicated Proton Therapy centers across India, uses a team-based, multidisciplinary approach to ensure each patient receives a personalized treatment plan with the highest chances of success.

Quality Assurance of Proton Therapy

Precision is everything in Proton Therapy, and Apollo Hospitals maintains strict quality assurance (QA) standards to ensure treatment accuracy and safety.

Key QA processes include:

• Daily calibration of the proton beam delivery system
• Patient-specific treatment plan verification before the first session
• Real-time imaging checks during each session to ensure alignment
• Ongoing data review by radiation oncologists and physicists

These protocols are aligned with global guidelines and audited regularly, making Apollo’s Proton Therapy not only precise but also among the safest in South Asia.

What Is the Cost of Proton Therapy in India?

At Apollo Proton Cancer Centre (APCC), the cost of Proton Therapy in India typically ranges from ₹25,00,000 to ₹50,00,000, depending on the type of cancer, treatment complexity, and overall care requirements. While it may be higher than conventional radiation, patients often find the investment worthwhile due to fewer long-term side effects, better organ preservation, and improved post-treatment quality of life.

What Factors Influence the Cost?

Several elements impact the overall treatment cost, including:

• Type and Stage of Cancer: More complex or rare tumors may require longer treatment duration and planning
• Treatment Duration: The number of proton sessions (fractions) varies depending on tumor size, location, and response
• Additional Therapies: Surgery, chemotherapy, immunotherapy, or advanced imaging may be combined with proton therapy
• Room Type and Stay: Choice between private or shared rooms, and length of hospital stay, if required
• Medical Complexity: Co-existing conditions or post-treatment complications may influence overall expenses

How Apollo Supports You Financially

Apollo Hospitals understands the financial challenges cancer treatment can bring. That’s why we offer a range of patient-friendly services to make the process as smooth and transparent as possible:

• Financial Counseling: Dedicated advisors explain cost breakdowns, assist with budgeting, and help you explore affordable options
• Insurance Support: Assistance with pre-authorizations, claim documentation, and coordination with insurers
• Transparent Estimates: Personalized cost quotes are provided before treatment begins—no hidden charges
• International Patient Services: Currency conversions, multilingual coordinators, and concierge support for global patients

More Affordable Than the West

Choosing Proton Therapy in India—especially at Apollo Proton Cancer Centre—offers world-class treatment at a fraction of the global cost:

• 40–60% more affordable than in the US, UK, or Europe
• Same technology platforms (including Pencil Beam Scanning and IMPT) used in top global cancer centers
• Personalized, end-to-end care under one roof

Get a Personalized Quote

Each patient’s treatment and financial needs are unique. We encourage you to contact Apollo Proton Cancer Centre for a customized estimate. Our expert team will walk you through:

• Medical eligibility
• Treatment plan
• Estimated cost
• Insurance approvals and billing process

Global Comparison: Proton Therapy in India vs Other Countries

Apollo Hospitals has brought world-class Proton Therapy to India, offering the same technology and outcomes as leading global cancer centers—but with faster access and at significantly lower costs.

Apollo Hospitals offers a global standard of care at a fraction of the cost—making India a preferred destination for Proton Therapy patients from across South Asia, the Middle East, Africa, and Europe.

Insurance Coverage

Proton Therapy is a relatively new technology in India, and insurance coverage may vary based on the policy and provider. Some insurance plans cover the treatment under their cancer care benefits, while others may require special approval or documentation.

Important Points

• Coverage depends on whether Proton Therapy is considered medically necessary
• Some insurers require prior authorization or evidence of superiority over conventional therapy
• Coverage may include only the treatment or also associated costs like hospital stay and imaging
• Apollo Hospitals has a dedicated insurance support team that assists patients with documentation, pre-approvals, and claim submissions

Patients are encouraged to consult with their insurance provider and hospital team early in the process to understand their eligibility and coverage limits.

Steps to Get a Second Opinion or Book a Consultation

If you or your loved one has been diagnosed with cancer and want to explore whether Proton Therapy is right for you, Apollo Hospitals makes it easy to take the next step.

How to Begin:

• Contact Apollo Proton Therapy Coordination Team through the hospital website or helpline: 1860-500-1066
• Send your medical reports (biopsy, imaging, diagnosis, previous treatment history)
• Get an expert review by our multidisciplinary oncology team
• Receive a second opinion report or personalized treatment plan within 48–72 hours
• Book a teleconsultation or in-person consultation
• Start your care journey with a dedicated coordinator who assists with scheduling, insurance, travel, and accommodation

Why It Matters:

• Get clarity on all available treatment options
• Make informed decisions backed by top oncologists
• Save time by streamlining the referral and treatment process

Apollo Hospitals offers this service to both domestic and international patients with no obligation to proceed unless you’re confident in the proposed plan.

Conclusion

Proton Therapy represents a major leap forward in cancer care, offering targeted treatment with fewer side effects and improved outcomes for many patients. Now available across multiple Apollo Hospitals in India—including Chennai, Hyderabad, Bangalore, Mumbai, Delhi, Kolkata, and Ahmedabad—it is making advanced cancer treatment more accessible than ever before.

If you or a loved one is exploring Proton Therapy, reach out to Apollo Hospitals today to schedule a consultation and take the first step toward safer, more precise cancer care.

Frequently Asked Questions (FAQs) – Proton Therapy at Apollo Hospitals

General Questions About Proton Therapy

• What is Proton Therapy and how is it different from regular radiation?
  Proton Therapy uses charged particles called protons instead of X-rays to target and destroy cancer cells. Unlike conventional radiation, the proton beam stops precisely at the tumor, reducing radiation exposure to healthy tissue and limiting side effects.
• Is Proton Therapy painful or invasive?
  No. Proton Therapy is non-invasive and completely painless. Patients lie on a treatment table while the beam is delivered. Each session typically lasts just a few minutes, and most patients resume daily activities afterward.
• How long does Proton Therapy treatment take?
  Treatment usually lasts four to seven weeks, with daily sessions from Monday to Friday. The exact duration depends on the cancer type and stage.
• Will I need to stay in the hospital for Proton Therapy?
  No. Proton Therapy is typically done on an outpatient basis. Patients return home the same day after each session.
• What should I expect after Proton Therapy ends?
  Most patients recover quickly and resume normal activities within a few weeks. Apollo Hospitals provides structured follow-up care, including imaging, lab tests, and specialist consultations.
• What are the side effects of Proton Therapy?
  Side effects are usually mild and depend on the treatment site. They may include fatigue, skin redness, or localized discomfort. Apollo provides individualized plans to manage any symptoms.
• Does hair grow back after Proton Therapy?
  Yes. Hair loss, if it occurs, is usually limited to the treatment area and is temporary. Hair generally begins to regrow within weeks to months after treatment ends.
• What is life like after Proton Therapy?
  Most patients return to their daily routines shortly after treatment. Long-term complications are minimal, and patients continue to receive monitoring and support from the Apollo care team.

Eligibility, Planning, and Safety

• Who is eligible for Proton Therapy?
  Patients with tumors near critical structures, pediatric cancers, or those needing re-irradiation are often suitable. Eligibility is determined by a multidisciplinary team at Apollo Hospitals.
• Who determines if Proton Therapy is appropriate for a patient?
  A multidisciplinary tumor board, including oncologists, radiologists, surgeons, and physicists, evaluates each case. Proton Therapy is recommended only when it provides clear benefits over other treatments.
• Is Proton Therapy safe for children?
  Yes. Proton Therapy is the safest radiation option for children. It reduces the risk of long-term complications like growth delays, organ damage, and secondary cancers.
• Can Proton Therapy be used if I’ve already had radiation therapy?
  Yes. Proton Therapy is often chosen for patients needing re-irradiation, as it delivers focused radiation to previously treated areas without excess exposure to surrounding tissues.
• Can proton therapy be combined with chemotherapy or surgery?
  Yes. Proton therapy is often used alongside chemotherapy or surgery, depending on the cancer type and stage. At APCC, a multidisciplinary team designs personalized treatment plans that may combine multiple therapies for better outcomes with minimal side effects.

Treatment Experience

• Can I get a second opinion on Proton Therapy?
  Yes. Apollo Hospitals offers expert second opinions. You can submit your medical reports online and receive a recommendation within 48 to 72 hours.
• How accessible is Proton Therapy in India?
  Proton Therapy is available at Apollo Hospitals in Chennai, Hyderabad, Bangalore, Mumbai, Delhi, Kolkata, and Ahmedabad. Wait times are usually short, with treatment starting within 1 to 2 weeks after evaluation.
• What support services are available during Proton Therapy?
  Apollo provides psychological counseling, nutrition advice, physiotherapy, pain management, and travel or accommodation support to ensure a smooth experience.
• Is it worth traveling to India for Proton Therapy?
  Yes. Apollo offers internationally accredited care at a significantly lower cost than in the US or Europe. Patients benefit from shorter wait times and advanced treatment technology.
• How is follow-up care handled after treatment at APCC?
  After treatment, APCC provides structured follow-up including clinical reviews, scans, and supportive care. Outstation and international patients can access follow-up through Apollo’s national network or virtual consultations, ensuring continuous monitoring and long-term wellness support.

Cost and Insurance

• How much does Proton Therapy cost in India?
  The cost ranges from ₹25,00,000 to ₹50,00,000 depending on the cancer type, treatment duration, room type, and other medical needs. Apollo offers transparent pricing and affordable care compared to global centers.
• Is Proton Therapy covered by insurance in India?
  Some insurance plans do cover Proton Therapy, especially when it is medically necessary. Apollo’s billing team assists with documentation, pre-authorizations, and claims.
• How does Proton Therapy in India compare to treatment abroad?
  Apollo Hospitals use the same advanced technology as leading centers in the US and Europe. Treatment in India is more affordable, accessible, and equally effective.
• Can Proton Therapy reduce the risk of secondary cancers?
  Yes. By limiting radiation exposure to healthy tissues, Proton Therapy reduces the risk of radiation-induced secondary cancers—an important consideration, especially for younger patients.

Proton Therapy by Cancer Type

Brain and Spine

• Can Proton Therapy be used for brain tumors?
  Yes. It is ideal for brain tumors because it precisely targets the tumor while sparing healthy brain tissue. This is especially important in both adults and children.
• Does Proton Therapy help treat spinal tumors?
  Yes. Proton beams can treat spinal tumors while minimizing damage to the spinal cord and nerves.
• Can children undergo Proton Therapy for cancer?
  Absolutely. It is the preferred method for pediatric cancers due to its accuracy and reduced risk of long-term effects.
• Is proton therapy beneficial for acoustic neuroma?
  Yes. Proton therapy helps preserve hearing and facial nerve function when treating acoustic neuromas.
• What is the role of proton therapy in treating ependymoma?
  Proton therapy is effective for ependymomas in the brain or spine, reducing complications and preserving neurological function.
• Is proton therapy used for glioblastoma?
  Yes, in selected or recurrent cases. It allows focused radiation delivery to aggressive tumor areas.
• Can proton therapy help in astrocytoma treatment?
  Yes. It minimizes radiation exposure to healthy brain tissue, reducing long-term neurological risks.
• Is oligodendroglioma treatable with proton therapy?
  Yes. It offers tumor control while preserving brain function and cognitive ability.
• Can AVMs (arteriovenous malformations) be treated with proton therapy?
  Yes, when surgery is not possible. Proton beams can shrink or close off abnormal blood vessels.
• How is pineoblastoma managed with proton therapy?
  Proton therapy treats this rare tumor while protecting developing brain tissue, especially in children.
• Can proton therapy be used for meningioma?
  Yes. It is very effective for meningiomas near the skull base or optic nerves.
• What advantages does proton therapy offer for pituitary tumors?
  It targets the tumor while preserving nearby brain and visual structures.

Head, Neck, and Oral Cancers

• Can Proton Therapy be used for head and neck cancers?
  Yes. It reduces radiation to salivary glands, spinal cord, and jaw, helping avoid long-term complications.
• Is proton therapy effective for nasal cavity cancers?
  Yes. It safely treats tumors in tight anatomical spaces, reducing damage to eyes and brain.
• Can proton therapy be used for paranasal sinus cancer?
  Yes. Its precision helps avoid damage to cranial nerves and vision-related structures.
• How does proton therapy help with nasopharyngeal carcinoma?
  It allows safe treatment of tumors near the skull base and optic nerves.
• Is proton therapy effective for oral cavity (mouth) cancers?
  Yes. It reduces side effects like dry mouth and jawbone damage while effectively treating the tumor.
• What are the benefits of proton therapy for cancers of the lip and mouth?
  It delivers effective doses with excellent cosmetic and functional outcomes.
• What are the proton therapy advantages for hypopharyngeal cancer?
  It minimizes radiation to the voice box and esophagus, preserving speech and swallowing.
• Why consider proton therapy for laryngeal (voice box) cancer?
  It allows precise targeting while protecting the vocal cords and surrounding tissues.
• How does proton therapy support salivary gland cancer treatment?
  It reduces radiation exposure to the jaw and facial nerves, helping preserve facial function.
• Is proton therapy beneficial for adenoid cystic carcinoma?
  Yes. Its precision is ideal for nerve-invading tumors like adenoid cystic carcinoma.
• What are the benefits of proton therapy for oropharyngeal cancer?
  It reduces radiation to the throat and swallowing structures, improving long-term outcomes.

Thoracic, Gastrointestinal, and Genitourinary Cancers

• Can Proton Therapy treat lung cancer?
  Yes. It targets lung tumors while sparing healthy lung tissue and the heart.
  
   
• Is Proton Therapy suitable for liver cancer?
  Yes. It can deliver high-dose radiation to liver tumors while protecting healthy tissue.
• Is Proton Therapy an option for pancreatic cancer?
  Yes, for selected cases. It allows safer delivery near sensitive organs like the stomach and intestines.
• Is Proton Therapy used for esophageal cancer?
  Yes. It reduces exposure to the heart and lungs, improving safety in complex cases.
• Does Proton Therapy help in prostate cancer treatment?
  Yes. It minimizes damage to the bladder and rectum, reducing urinary and bowel side effects.
• Is proton therapy commonly used for prostate cancer?
  Yes. It is a well-established treatment option offering excellent tumor control and fewer complications.

Other Questions

• Why is proton therapy ideal for skull base tumors?
  These tumors are close to critical nerves and vessels. Proton therapy treats them precisely with minimal complications.
• Can proton therapy treat an acoustic neuroma?
  Yes. Proton therapy is often used for acoustic neuromas (vestibular schwannomas), especially when the tumor is close to the hearing or facial nerves. Its precision helps preserve hearing and facial movement while effectively controlling the tumor.
• Is proton therapy beneficial for adenoid cystic carcinoma?
  Yes. Proton therapy is especially helpful for adenoid cystic carcinoma, which often follows nerve pathways. The precision of proton beams allows delivery of high-dose radiation while protecting nearby critical nerves and tissues.
• How does proton therapy help in astrocytoma treatment?
  Proton therapy minimizes exposure to healthy brain tissue when treating astrocytomas. This is particularly important in children and young adults, where long-term brain function and cognitive ability must be preserved.
• Can AVMs (arteriovenous malformations) be treated with proton therapy?
  Yes, in select cases. When surgery is not an option, proton therapy can help close off or shrink arteriovenous malformations in the brain while minimizing radiation to surrounding tissue.